ePILOT Bioreactor

Pilot scale bioreactor with leading technology and flexibility
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Overview

Optimizing bioprocessing outcomes with innovative engineering and precise regulation.

The ePILOT® is made of stainless steel AISI 304 and 316L. It is a crucial tool in upstream processes, providing exceptional productivity in both cell culture and microbial fermentation. Its design, crafted to meet diverse client demands, prioritises efficient culture growth and offers various vessel sizes for seamless scale-up productions.

Integrating a PLC into our bioreactor improves bioprocessing success by providing flexible programming, ensuring a comprehensive understanding of each stage of the process.

Our pilot scale bioreactor features advanced monitoring systems. These systems enable the real-time tracking of crucial parameters like pH, pO2, temperature, and foam levels. This tracking ensures ideal conditions for the growth and development of cells and microorganisms.

 

Key strategies for effective scalability in pilot scale bioreactors

TECNIC ePILOT® bioreactor offers a unique solution in scalability and adaptability, allowing for the interchangeability of vessels between the cellular and microbial versions. Essential for laboratories and production plants, seeking flexibility in their cell culture and microbial fermentation processes.

With working volumes of 10, 20, 30, and 50 liters, the interchangeable vessels of the ePILOT® facilitate the transition between different scales of production or research, without the need to invest in multiple systems. The bioreactor is dedicated to precision and adaptability, with real-time monitoring through integrated sensors.

Key components include: external jacket, sparger, overlay gas inlets, rupture disc, addition valves, and ports for sensors, sampling kit, a bottom valve and a front-integrated sight glass allows monitoring of crucial parameters like turbidity and agitation.

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Brochure ePILOT Bioreactor
The vessel design of the ePILOT Bioreactor is ideal for versatile volume adjustments in bioprocess. Furthermore, it enables the customization of equipment features, to meet user needs by exchanging different vessels, providing an excellent solution for scaling up production (10L, 20L, 30L and 50 L). The vessel is manufactured with stainless steel, regarding an aspect ratio of 1:3 (diameter: height) for microbial culture and 1:2 for cell culture.
With a 15-inch touch screen interface, our pilot scale bioreactor provides an intuitive control system. This system facilitates the monitoring and adjustment of key parameters in culture growth, ensuring maximum accuracy in the process.
Composed of a set of digital sensors, our system controls and monitors pH, pO2, temperature, and level/foam in real-time. This level of oversight is a cornerstone in achieving high-quality biotechnological outcomes, which guarantees optimal conditions for the growing and development of both cells and microorganism.
With the ePILOT Bioreactor, we achieve maximum hygiene and sterilization through steam with the included ‘External SIP version.’ For facilities unable to generate vapor, an “AUTOSIP version” is available, integrating electric resistances within the equipment to generate vapor.
Our equipment provides two precision-controlled impellers: the 6-blade Rushton turbine for microbial fermentation and the 3-pitched blade for cell culture. Governed by a servomotor, these impellers maximize efficiency and productivity by adjusting agitation velocity and intensity, delivering a power of 400W for optimal bioprocessing performance.

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  • 6603 BN Wijchen
  • The Netherlands

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