Opentrons Flex Workstation

Automated liquid handling and workstation
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Overview

The next generation of lab automation is here.

Flex fits you, not the other way around.

Opentrons Flex is everything today’s lab automation systems are not. It’s flexible, versatile and liberating.

  • Uniquely flexible: Modular pipettes, gripper, and on-deck hardware that you can swap out yourself
  • Uniquely open: Fully open source software and firmware
  • Uniquely future-facing: Extensive API compatible with “design-of-experiment” programs, including AI-driven agents
  • Touchscreen for easy protocol set-up: Select and run protocols directly from the lab bench using the touchscreen. It also guides you through deck setup and automated calibration.

 

Upgraded software

Quick Transfer

Use the Opentrons Flex for individual pipetting steps in manual protocols, e.g. reagent addition, dilutions, and cherrypicking – single steps can now be initiated with a few touchscreen taps.

Liquid Level Detection

You know not to immerse your pipette tip too far in a liquid, and now Flex robots know too. Pressure sensors already installed on all Flex robots now have the capability to detect when pipette tips make contact with liquids, which is especially important when pipetting from 15mL or 50mL tubes.

CSV File Integration

For those complicated pipetting tasks that don’t use every well or change volume between wells, .csv file integration is now a breeze using either the computer or from the Flex touchscreen. Simply send a file to the robot and run without having to integrate into a protocol.

Partial Tip Pickup

Use a multi-channel pipette as a single channel: by picking up a single tip, a multi-channel pipette can be used as a single channel pipette. Ideal for when wells need different volumes, or aspirations/dispenses are desired from a single well. This new feature also allows the use of any number of channels to be used with an 8-channel pipette, and any number of columns to be used on a 96-channel pipette.

Downloads

Brochure Opentrons Flex
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With the Flex NGS Workstation, you can automate NGS library prep at the scale you need to increase efficiency, reduce errors, and save hands-on time. Automate all your pre-sequencing workflows using any leading reagent system, including fragmentation- and tagmentation-based library prep, on the market.
With the Flex PCR Workstation, you can fully automate your PCR setup and thermocycling workflow for up to 96 samples. Aliquot chilled reagents and samples into a 96-well PCR plate, use the Flex Gripper to load the plate into the on-deck thermocycler on the Flex deck, and then run your chosen PCR program.
With the Flex Magnetic Bead Protein Purification Workstation, you can automate small-scale protein purification and proteomics sample prep for up to 96 samples. This workstation is compatible with many popular magnetic bead-based reagents.
With the Flex Nucleic Acid Extraction Workstation, you can automate DNA/RNA isolation and purification. This workstation comes with the Flex Magnetic Block for separation of magnetic beads, and the Opentrons Heater-Shaker for sample lysis and resuspension of magnetic beads.

Workflow Monoclonal antibody production

1

Immunization of animal

2

Isolation of B-cells

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3

Single B-Cell Dispensing in lysisbuffer

Cytena F.Sight Omics
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4

cDNA production and amplification

Opentrons Flex
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5

Plasmid ligation & amplicon insertion

Opentrons Flex
6

Start of culture

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  • The Netherlands

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